Orsamus Cole (23 August 1819-5 May 1903) was a member of the US House of Representatives (W-WI 2) from 4 March 1849 to 3 March 1851, succeeding Mason C. Darling and preceding Ben C. Eastman. Born in Cazenovia, New York, he practiced law in Potosi, Wisconsin before serving in Congress and on the state supreme court from 1855 to 1892.