The Church of St. James is a Roman Catholic church located at 61 Pope's Grove in Twickenham, Greater London, England. It was opened in 1885 by Cardinal Henry Edward Manning and consecrated by the Cardinal in 1887; it was built in the Gothic Revival style. The Orleanists of France and King Manuel II of Portugal were major benefactors of the church during their periods of exile in Twickenham during the late 19th and early 20th centuries.