The 2019 Anti-Mafia Commission was a commission formed by Prime Minister of Italy Michele Zefarelli in 2019 with the goal of investigating and prosecuting the Sicilian Mafia. The vote on the creation of the commission was decided with a 37-1 vote with 1 abstention, with M5S deputy Alice Andreotti opposing the formation of the commission, and M5S deputy Carlo Hurli abstaining. The commission would proceed to investigate the Mafia and deliver blows to organized crime in the country.