Joao Manuel, Prince of Portugal

Joao Manuel, Prince of Portugal (3 June 1537-2 January 1554) was a Portuguese infante, the son of King Joao III of Portugal and Catherine of Austria. He was also the father of King Sebastian of Portugal with Joan of Spain.

Biography
Joao Manuel was born in Evora, Portugal on 3 June 1537, the son of King Joao III of Portugal and Catherine of Austria. He became heir to the throne at the age of two, and he survived his four older brothers, although he was a sickly teenager. In 1552, he married his first cousin Joan of Spain, and he died of tuberculosis two years later. His only child would become King Sebastian of Portugal.