Marcantonio Colonna

Marcantonio I Colonna (1478-1522) was the Lord of Frascati, a condottiero, and a member of the powerful House of Colonna. Colonna married the niece of Pope Julius II, who he later fought against as a general of the Republic of Venice and France. He was killed during Spain's 1522 siege of Milan.

Biography
Marcantonio Colonna was the nephew of Prospero Colonna and a member of the powerful Colonna family of Rome, and he started his military career at the age of 24. Colonna became a renowned condottiero, serving the Republic of Florence in 1502 and Pope Julius II afterwards. After marrying Pope Julius' niece, he was made Lord of Frascati. Colonna distinguished himself fighting for the Republic of Venice and France against the Pope during the War of the League of Cambrai, and he organized the 1522 defense of Milan against Spain. While inspecting the front lines, he was mortally wounded by a cannon shell.